Go to Top
INVENTOR LOGIN

Details

Project TitleCardiac Biomarker Sensing Based on Nanofluidic Amplification and Resonant Optical Detection
Track Code2010-093
Short Description

This novel invention is a compact, integrated sensor consisting of several technologies on a single chip to detect ultra-low concentrations of biomarkers with high sensitivity.

Abstract

This novel invention is a compact, integrated sensor consisting of several technologies on a single chip to detect ultra-low concentrations of biomarkers with high sensitivity. Specifically, the lab-on-a-chip sensor platform has been developed to detect multiple cardiac biomarkers from microliter bloods samples.

 
TagsCardiac Biomarker, diagnostic, Nanochannel, Optical Sensors
 
Posted DateJun 14, 2013

Researcher

Name
Sang Han
Cornelius Ivory
Mani Hossein-Zadeh

Manager

Name
Briana Wobbe

Background

Over 1.2 million new and recurrent heart attacks are diagnosed in the US every year. More than 500,000 of these patients will die within a year and, of these, about half will die within 1 hour of the appearance of symptoms. While emergency medical technicians, paramedics, and emergency room physicians could begin treating cardiac arrhythmias that are diagnosed in the first, "golden" hour following a heart attack, most people ignore symptoms for more than 2 hours, and many delay treatment for more than 12 hours. An accurate, portable and fast biomarker diagnostic would facilitate field diagnoses and would also allow on-the-spot detection of coronary disease during routine clinical visits.

Technology Description

This novel invention is a compact, integrated sensor consisting of several technologies on a single chip to detect ultra-low concentrations of biomarkers with high sensitivity. Specifically, the lab-on-a-chip sensor platform has been developed to detect multiple cardiac biomarkers from microliter bloods samples.

Advantages/Applications

  • Accurate, portable and fast biomarker diagnostic
  • Allows for field diagnoses by facilitating real-time monitoring of cardiac biomarkers
  • Allows for detection of coronary disease during routine clinical visits
  • Inexpensive, highly versatile and compact with low power consumption
  • Transferable to other trace biomarkers
  • Requires minimal training to use the fully automated device
  • Determines concentration of different biomarkers in parallel on a single chip
  • Detects ultra-low concentrations of biomarkers with a sensitivity down to 1 nanogram/microleter
  • Helps in the development of a rapid point-of-care platform for myocardial diseases
  • Overcomes disadvantages of the conventional methods by providing continuous quantitative, fast, high-throughput, label-free, highly targeted detection of sub- concentrations of cardiac biomarkers

 Applications:

  • Biomedical devices
  • Can be used to detect a variety of biomarkers
  • Nanofluidic sensing systems

Publications

INQUIRES

STC has filed intellectual property on this exciting new technology and is currently exploring commercialization options. If you are interested in information about this or other technologies, please contact Arlene Mirabal at amirabal@stc.unm.edu or 505-272-7886.

Files

File Name Description
US-2015-0024507-A1 Published Patent Application None Download