Discovering the complex mechanisms behind a wide
range of biological processes and human diseases starts with understanding the
functions of cellular proteins.
Enhancing our knowledge of these proteins can also contribute
significantly to the development of novel therapies and diagnostics, two major
goals of biomedical research. A related
branch of technology that allows investigators to modify or label chosen
proteins with specific functionalities or probes in living cells is key in
achieving these goals. Various methods
already exist and are used to modify and label proteins of choice, and these
provide unparalleled labeling specificity and are easily applied to and used in
the studies of various biological processes.
While these techniques have proven to be effective, they have their
share of problems and limitations. One
major barrier that keeps these methods from obtaining a more general use is
their limited targeting specificity and coupling efficiency in attaching these
probes to chosen proteins within the cell.
A technology void of this problem would be ideal and would make the use
of probes to monitor and manipulate specific proteins within a cell more
efficient as well as more widely applicable.
A researcher at the University of New Mexico has
developed a novel technology that can be used to monitor or manipulate any
chosen cellular protein with a large variety of synthetic chemical probes for
various biological and biomedical applications.
The developed protein-labeling system is proximity-assisted, enabling
the insertion of chemical probes with high efficiency and specificity. This technology addresses multiple
limitations associated with current methods and provides a superior and more
broadly applicable protein-labeling platform.
STC has filed intellectual property on this exciting new technology and is currently exploring commercialization options. If you are interested in information about this or other technologies, please contact Arlene Mirabal at firstname.lastname@example.org or 505-272-7886.